A recent study in the New England Journal of Medicine revealed that drug companies selectively publish the positive studies on antidepressants, but not those with negative results. (Turner EH, et al. NEJM 2008). Even the "positive" results aren't all that positive. A 50% improvement in half the symptoms is considered a positive outcome, and this minimal result is achieved in less than half the patients taking these medications. Plus, 86% of those who experience some relief from depression also experience side-effects including sexual dysfunction, fatigue, insomnia, loss of mental abilities, nausea and weight gain.